Clot-Busting Drug May Help Treat Frostbite: Easing blood flow avoids amputations, researchers say
"Based on the dramatic improvements in perfusion and reduction in rates of amputations when tPA was administered within 24 hours of frostbite injury, we anticipate the continued use of tPA in patients who are admitted to our institution with acute frostbite."
- Study authors
Los Angeles, California, USA - A powerful clot-busting drug used in stroke and heart attack patients might also reduce amputations in people with severe frostbite, researchers say.
Bruen suspects that tPA works by reducing injury caused when frozen skin is re-warmed.